SEVERE COLD AND FLU

NDC 51316-533, acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride, solution, from CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED.

Product NDC: 51316-533
Status: Listed
Labeler: CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Dosage form: SOLUTION
Route: ORAL
Product type: HUMAN OTC DRUG
Marketing category: OTC MONOGRAPH DRUG
Application: M012
DEA schedule: None

Request

curl https://api.healthcare.dev/v1/drugs/ndc/51316-533 \
  -H "Authorization: Bearer $HDEV_API_KEY"

Product

Active ingredients and packages

Active ingredients

ACETAMINOPHEN325 mg/15mL
DEXTROMETHORPHAN HYDROBROMIDE10 mg/15mL
DOXYLAMINE SUCCINATE6.25 mg/15mL
PHENYLEPHRINE HYDROCHLORIDE5 mg/15mL

Pharmacologic classes

Adrenergic alpha1-Agonists [MoA]; Antihistamine [EPC]; Histamine Receptor Antagonists [MoA]; Sigma-1 Agonist [EPC]; Sigma-1 Receptor Agonists [MoA]; Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]; Uncompetitive NMDA Receptor Antagonists [MoA]; alpha-1 Adrenergic Agonist [EPC]

Package NDC	NDC-11	Package
51316-533-40	51316053340	355 mL in 1 BOTTLE (51316-533-40)

Linked data

RxNorm, label and prices

RxNorm concepts

1431245acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / doxylamine succinate 0.417 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution (SCD)

Related lookups

No FDA label, Medicare Part B payment limit or NADAC price is linked to this product.

Use it

Look up 51316-533 from code or an agent

curl

curl https://api.healthcare.dev/v1/drugs/ndc/51316-533 \
  -H "Authorization: Bearer $HDEV_API_KEY"

MCP prompt

Using the healthcare.dev MCP server, look up NDC 51316-533. Tell me the product, its labeler, dosage form and route, its packages, and the RxNorm concepts it maps to.

Get a free key NDC docs Connect the MCP server

Source: FDA, release 2026-10-23. Public domain. Reference data, not medical advice.